Business outline

Kawasumi is the world's first company to commercialize the system of double filtration plasmapheresis (DFPP) in 1983. Since then Kawasumi has been continually engaged in the plasmapheresis industry, mainly by OEM production.

In 2009, Kawasumi took over Kuraray Medical Inc.'s sales license for both domestic and overseas markets. Our business interests cover product development all the way through to sales and marketing.

Plasmapheresis is the therapeutic approach to the removal of pathogenic factors from patients' blood by extracorporeal circulation. There are various methods of removing pathogenic factors, such as filtration, dialysis, adsorption, etc. and the appropriate one is selected based on the chemo-physical property of the substances to be removed. Therapeutic plasmapheresis is applied to various diseases whose symptom is expected to be improved by removing particular substances exist in blood.

Kawasumi Laboratories is currently, and will continue to be, exploring further effective procedures and potential indications of the therapy through the collaborative research with various institutes in worldwide.


Which product is suitable for your target substances to be removed by Plasmapheresis ?

Plasma Fractionator Evaflux™
"For Double Filtration Plasmapheresis (DFPP)
targeting on high molecular weight plasma components"
  • Selective depletion of plasma components based on their molecular size
  • Reduced or no requirement for substitution fluid
  • Wide range of applications
Indications (Example):
  • Familial Hypercholesterolemia
  • ABO/HLA incompatible Kidney transplantation
  • Myasthenia Gravis

Plasma Separator Evacure™ / Evaclio™

*There are two trade names for the same plasma separator : Evacure™ and Evaclio™. Either name is used depends on the country.

“For High-volume Selective Plasma Exchange”
  • Smaller loss of high-molecular-weight substances
  • Plasma substitute fluid saving
  • 4 types of membrane with different permeability are available depends on the target substances
Indications (Example):
  • Hepatic Failure
  • Sepsis

Plasma Separator Plasmacure™PE
“Stable filtration property for plasma separation”
  • Ethylene vinyl alcohol copolymer, a hydrophilic material, is coated on the surface of polyethylene hollow fibers
  • Gamma ray sterilized / ETO free
  • Filtration property is stable due to less TMP increase


Plasmapheresis System KM-9000

* This product is not CE marked.

"For various treatment procedure, with various functions for safety and usability" Features:
  • Applicable for multiple treatment procedure
    Plasma Exchange, Plasma Perfusion, DFPP, DF Thermo®,
    Direct Hemoperfusion
    CRRT, ECUM, Cell-free and Concentrated Ascites Reinfusion Therapy
  • Functions for safety and usability
    Auto priming and blood recovery, Auto checking of blood tubing connection Color display with touch panel, etc.
  • Panel-type blood tubing sets for easy setting and avoiding mis-setting

*Please read the instruction carefully before use.

For more information, click here to visit KAWASUMI Plasmapheresis site;